Выпускники кафедры генетики и селекции

Dmitri Ivanov

Curriculum Vitae

1986-1992    Diploma student, Laboratory of Pr. S.G. Inge-Vechtomov, Department of Genetics and Selection, St. Petersburg University, St. Petersburg, Russia.
Diploma “Nuclear Antisuppressor Mutations Restoring Respiratory Competence of the sup 45 Mutants of Yeast Saccharomyces cerevisiae”

1992-1995    Ph.D. student, Laboratory of Dr. M. Bennett, University of Texas Southwestern Medical Center at Dallas, TX, USA.

1995-1999    Ph.D. student, Laboratory of Dr. R. B. Gaynor, University of Texas Southwestern Medical Center at Dallas, TX, USA

Ph.D. Thesis “Tat-Associated Kinases and Their Role in the Regulation of HIV Transcription”

2000-2006     Postdoc, laboratory of Dr. K. Nasmyth,  Institute of Molecular Pathology, Vienna, Austria.

November 2006    Independent junior research group leader, Friedrich Miescher   Laboratory, Max Planck Society, Tuebingen, Germany

Publications:

• Garcia-Martinez, L.F., Ivanov, D., and Gaynor, R.B. (1997) Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes. J. Biol. Chem. 272, 6951-6958.

• Garcia-Martinez, L.F., Mavankal, G., Neveu, J.M., Lane, W.S., Ivanov, D., and Gaynor, R.B. (1997) Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription. EMBO J. 16, 2836-2850.

• Ivanov, D., Kwak, Y.T., Nee, E., Guo, J., Garcia-Martinez, L.F., and Gaynor, R.B. (1999) Cyclin T domains involved in complex formation with Tat and TAR RNA are critical for Tat-transactivation. J. Mol. Biol. 288, 41-56.

• Kwak, Y.T., Ivanov, D., Guo, J., Nee, E., and Gaynor, R.B. (1999) Role of the human and murine cyclin T proteins in regulating HIV-1 Tat-activation. J. Mol. Biol. 288, 57-69.

• Ivanov, D., Kwak, Y.T., Guo, J., and Gaynor, R.B. (2000) Domains in the SPT5 protein that modulate its transcriptional regulatory properties. Mol. Cell. Biol. 20, 2970-2983.

• Ivanov, D., Schleiffer, A., Eisenhaber, F., Mechtler, K., Haering, C.H. and Nasmyth, K. (2002) Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Current Biology 12, 323-328.

• Ivanov, D., and Nasmyth, K. (2005) A topological interaction between cohesin rings and a circular minichromosome. Cell 122, 849-860.

• Ivanov, D., and Nasmyth, K (2007) A physical assay for sister chromatid cohesion in vitro. Mol. Cell 27, 300-310.

I am interested in the mechanisms of sister chromatid cohesion and chromosome segregation. We use yeast Saccharomyces cerevisiae as the model organism and methods ranging from biochemistry to electron microscopy to obtain insights into these interconnected processes which lie at the core of cell division.